Regulatory T Cells Resist Cyclosporine-Induced Cell Death via CD44-Mediated Signaling Pathways

Cyclosporine A (CSA) is an immunosuppressive agent that specifically targets T cells and also increases the percentage of pro-tolerogenic CD4+Foxp3+ regulatory T cells (Treg) through unknown mechanisms. We previously reported that CD44, a receptor for the extracellular matrix glycosaminoglycan hyalu...

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Veröffentlicht in:Int J Cell Biol
Hauptverfasser: Ruppert, Shannon M., Falk, Ben A., Long, S. Alice, Bollyky, Paul L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581548/
https://ncbi.nlm.nih.gov/pubmed/26448755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/614297
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