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Hyaluronan Synthase: The Mechanism of Initiation at the Reducing End and a Pendulum Model for Polysaccharide Translocation to the Cell Exterior

Hyaluronan (HA) biosynthesis has been studied for over six decades, but our understanding of the biochemical details of how HA synthase (HAS) assembles HA is still incomplete. Class I family members include mammalian and streptococcal HASs, the focus of this review, which add new intracellular sugar...

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Detalhes bibliográficos
Publicado no:Int J Cell Biol
Autor principal: Weigel, Paul H.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581545/
https://ncbi.nlm.nih.gov/pubmed/26472958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/367579
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