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Correlating RANK Ligand/RANK Binding Kinetics with Osteoclast Formation and Function
The interaction between Receptor Activator of NF-κB Ligand (RANKL) and its receptor RANK is essential for the differentiation and bone resorbing capacity of the osteoclast. Osteoprotegerin (OPG), a soluble homodimer, acts as a decoy receptor for RANKL and thus inhibits osteoclastogenesis. An imbalan...
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| Publié dans: | J Cell Biochem |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4581524/ https://ncbi.nlm.nih.gov/pubmed/25864714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25191 |
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