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Correlating RANK Ligand/RANK Binding Kinetics with Osteoclast Formation and Function

The interaction between Receptor Activator of NF-κB Ligand (RANKL) and its receptor RANK is essential for the differentiation and bone resorbing capacity of the osteoclast. Osteoprotegerin (OPG), a soluble homodimer, acts as a decoy receptor for RANKL and thus inhibits osteoclastogenesis. An imbalan...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Warren, Julia T., Zou, Wei, Decker, Corinne E., Rohatgi, Nidhi, Nelson, Christopher A., Fremont, Daved H., Teitelbaum, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581524/
https://ncbi.nlm.nih.gov/pubmed/25864714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25191
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