Potential Effects of Phytoestrogen Genistein in Modulating Acute Methotrexate Chemotherapy-Induced Osteoclastogenesis and Bone Damage in Rats

Chemotherapy-induced bone damage is a frequent side effect which causes diminished bone mineral density and fracture in childhood cancer sufferers and survivors. The intensified use of anti-metabolite methotrexate (MTX) and other cytotoxic drugs has led to the need for a mechanistic understanding of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: King, Tristan J., Shandala, Tetyana, Lee, Alice M., Foster, Bruce K., Chen, Ke-Ming, Howe, Peter R., Xian, Cory J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581246/
https://ncbi.nlm.nih.gov/pubmed/26258775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160818293
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