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Methotrexate Toxicity in Growing Long Bones of Young Rats: A Model for Studying Cancer Chemotherapy-Induced Bone Growth Defects in Children

The advancement and intensive use of chemotherapy in treating childhood cancers has led to a growing population of young cancer survivors who face increased bone health risks. However, the underlying mechanisms for chemotherapy-induced skeletal defects remain largely unclear. Methotrexate (MTX), the...

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Detalhes bibliográficos
Main Authors: Fan, Chiaming, Georgiou, Kristen R., King, Tristan J., Xian, Cory J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085506/
https://ncbi.nlm.nih.gov/pubmed/21541196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/903097
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