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A Single Nucleotide Polymorphism near the CYP17A1 Gene Is Associated with Left Ventricular Mass in Hypertensive Patients under Pharmacotherapy

Cytochrome P450 17A1 (CYP17A1) catalyses the formation and metabolism of steroid hormones. They are involved in blood pressure (BP) regulation and in the pathogenesis of left ventricular hypertrophy. Therefore, altered function of CYP17A1 due to genetic variants may influence BP and left ventricular...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Huber, Matthias, Lezius, Susanne, Reibis, Rona, Treszl, Andras, Kujawinska, Dorota, Jakob, Stefanie, Wegscheider, Karl, Völler, Heinz, Kreutz, Reinhold
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581202/
https://ncbi.nlm.nih.gov/pubmed/26263970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160817456
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