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A Single Nucleotide Polymorphism near the CYP17A1 Gene Is Associated with Left Ventricular Mass in Hypertensive Patients under Pharmacotherapy

Cytochrome P450 17A1 (CYP17A1) catalyses the formation and metabolism of steroid hormones. They are involved in blood pressure (BP) regulation and in the pathogenesis of left ventricular hypertrophy. Therefore, altered function of CYP17A1 due to genetic variants may influence BP and left ventricular...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Huber, Matthias, Lezius, Susanne, Reibis, Rona, Treszl, Andras, Kujawinska, Dorota, Jakob, Stefanie, Wegscheider, Karl, Völler, Heinz, Kreutz, Reinhold
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581202/
https://ncbi.nlm.nih.gov/pubmed/26263970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160817456
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