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Peto's paradox and the hallmarks of cancer: constructing an evolutionary framework for understanding the incidence of cancer
An evolutionary perspective can help unify disparate observations and make testable predictions. We consider an evolutionary model in relation to two mechanistic frameworks of cancer biology: multistage carcinogenesis and the hallmarks of cancer. The multistage model predicts that cancer risk increa...
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| Veröffentlicht in: | Philos Trans R Soc Lond B Biol Sci |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Royal Society
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4581038/ https://ncbi.nlm.nih.gov/pubmed/26056359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2015.0161 |
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