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Peto's paradox and the hallmarks of cancer: constructing an evolutionary framework for understanding the incidence of cancer
An evolutionary perspective can help unify disparate observations and make testable predictions. We consider an evolutionary model in relation to two mechanistic frameworks of cancer biology: multistage carcinogenesis and the hallmarks of cancer. The multistage model predicts that cancer risk increa...
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| Publicado en: | Philos Trans R Soc Lond B Biol Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Royal Society
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4581038/ https://ncbi.nlm.nih.gov/pubmed/26056359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2015.0161 |
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