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Solutions to Peto's paradox revealed by mathematical modelling and cross-species cancer gene analysis
Whales have 1000-fold more cells than humans and mice have 1000-fold fewer; however, cancer risk across species does not increase with the number of somatic cells and the lifespan of the organism. This observation is known as Peto's paradox. How much would evolution have to change the parameter...
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| Udgivet i: | Philos Trans R Soc Lond B Biol Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4581027/ https://ncbi.nlm.nih.gov/pubmed/26056366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0222 |
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