The Dihydrofolate Reductase 19 bp Polymorphism Is Not Associated with Biomarkers of Folate Status in Healthy Young Adults, Irrespective of Folic Acid Intake(1)(2)(3)

Background: Dihydrofolate reductase (DHFR) is essential for the conversion of folic acid to active folate needed for one-carbon metabolism. Common genetic variation within DHFR is restricted to the noncoding regions, and previous studies have focused on a 19 bp deletion/insertion polymorphism (rs709...

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Bibliographische Detailangaben
Veröffentlicht in:J Nutr
Hauptverfasser: Ozaki, Mari, Molloy, Anne M, Mills, James L, Fan, Ruzong, Wang, Yifan, Gibney, Eileen R, Shane, Barry, Brody, Lawrence C, Parle-McDermott, Anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Nutrition 2015
Schlagworte:
Biochemical, Molecular, and Genetic Mechanisms
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580961/
https://ncbi.nlm.nih.gov/pubmed/26269242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.115.216101
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