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Disinhibitory Action of Astrocytic GABA at the Perforant Path to Dentate Gyrus Granule Neuron Synapse Reverses to Inhibitory in Alzheimer's Disease Model

Like neurons, astrocytes produce and release GABA to influence neuronal signaling. At the perforant path to dentate gyrus granule neuron synapse, GABA from astrocyte was found to be a strong inhibitory factor, which impairs synaptic transmission, synaptic plasticity and memory in Alzheimer's di...

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Detalles Bibliográficos
Publicado en:Exp Neurobiol
Main Authors: Yarishkin, Oleg, Lee, Jaekwang, Jo, Seonmi, Hwang, Eun Mi, Lee, C. Justin
Formato: Artigo
Idioma:Inglês
Publicado: The Korean Society for Brain and Neural Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580748/
https://ncbi.nlm.nih.gov/pubmed/26412970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5607/en.2015.24.3.211
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