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Systematic assessment of imputation performance using the 1000 Genomes reference panels

Genotype imputation has been widely adopted in the postgenome-wide association studies (GWAS) era. Owing to its ability to accurately predict the genotypes of untyped variants, imputation greatly boosts variant density, allowing fine-mapping studies of GWAS loci and large-scale meta-analysis across...

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Bibliographische Detailangaben
Veröffentlicht in:Brief Bioinform
Hauptverfasser: Liu, Qian, Cirulli, Elizabeth T., Han, Yujun, Yao, Song, Liu, Song, Zhu, Qianqian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580532/
https://ncbi.nlm.nih.gov/pubmed/25246238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbu035
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