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Inclusion of Population-specific Reference Panel from India to the 1000 Genomes Phase 3 Panel Improves Imputation Accuracy

Imputation is a computational method based on the principle of haplotype sharing allowing enrichment of genome-wide association study datasets. It depends on the haplotype structure of the population and density of the genotype data. The 1000 Genomes Project led to the generation of imputation refer...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ahmad, Meraj, Sinha, Anubhav, Ghosh, Sreya, Kumar, Vikrant, Davila, Sonia, Yajnik, Chittaranjan S., Chandak, Giriraj R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532257/
https://ncbi.nlm.nih.gov/pubmed/28751670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06905-6
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