Antagonism of angiotensin 1–7 prevents the therapeutic effects of recombinant human ACE2

Activation of the angiotensin 1–7/Mas receptor (MasR) axis counteracts angiotensin II (Ang II)-mediated cardiovascular disease. Recombinant human angiotensin-converting enzyme 2 (rhACE2) generates Ang 1–7 from Ang II. We hypothesized that the therapeutic effects of rhACE2 are dependent on Ang 1–7 ac...

Full description

Saved in:
Bibliographic Details
Published in:J Mol Med (Berl)
Main Authors: Patel, Vaibhav B., Takawale, Abhijit, Ramprasath, Tharmarajan, Das, Subhash K., Basu, Ratnadeep, Grant, Maria B., Hall, David A., Kassiri, Zamaneh, Oudit, Gavin Y
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580513/
https://ncbi.nlm.nih.gov/pubmed/25874965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-015-1285-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items