Designing and Implementing an Assay for the Detection of Rare and Divergent NRPS and PKS Clones in European, Antarctic and Cuban Soils

The ever increasing microbial resistome means there is an urgent need for new antibiotics. Metagenomics is an underexploited tool in the field of drug discovery. In this study we aimed to produce a new updated assay for the discovery of biosynthetic gene clusters encoding bioactive secondary metabol...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Amos, Gregory C. A., Borsetto, Chiara, Laskaris, Paris, Krsek, Martin, Berry, Andrew E., Newsham, Kevin K., Calvo-Bado, Leo, Pearce, David A., Vallin, Carlos, Wellington, Elizabeth M. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580463/
https://ncbi.nlm.nih.gov/pubmed/26398766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138327
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