PTEN loss is associated with follicular variant of Middle Eastern papillary thyroid carcinoma

BACKGROUND: PTEN gene at chromosomes 10q23.3 is a tumour suppressor gene that is inactivated in many types of human cancers. The known mechanisms of PTEN inactivation are rendered to mutation, epigenetic silencing by aberrant methylation or gene deletion. Although PTEN role has been documented in ma...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Beg, S, Siraj, A K, Jehan, Z, Prabakaran, S, Al-Sobhi, S S, Al-Dawish, M, Al-Dayel, F, Al-Kuraya, K S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580399/
https://ncbi.nlm.nih.gov/pubmed/25989274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.169
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