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The Structure of Immature Virus-Like Rous Sarcoma Virus Gag Particles Reveals a Structural Role for the p10 Domain in Assembly

The polyprotein Gag is the primary structural component of retroviruses. Gag consists of independently folded domains connected by flexible linkers. Interactions between the conserved capsid (CA) domains of Gag mediate formation of hexameric protein lattices that drive assembly of immature virus par...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Schur, Florian K. M., Dick, Robert A., Hagen, Wim J. H., Vogt, Volker M., Briggs, John A. G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580193/
https://ncbi.nlm.nih.gov/pubmed/26223638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01502-15
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