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Nucleic Acid Binding-Induced Gag Dimerization in the Assembly of Rous Sarcoma Virus Particles In Vitro
As also found for other retroviruses, the Rous sarcoma virus structural protein Gag is necessary and sufficient for formation of virus-like particles (VLPs). Purified polypeptide fragments comprising most of Gag spontaneously assemble in vitro at pH 6.5 into VLPs lacking a membrane, a process that r...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2004
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC303394/ https://ncbi.nlm.nih.gov/pubmed/14671087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.52-60.2004 |
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