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Nucleic Acid Binding-Induced Gag Dimerization in the Assembly of Rous Sarcoma Virus Particles In Vitro

As also found for other retroviruses, the Rous sarcoma virus structural protein Gag is necessary and sufficient for formation of virus-like particles (VLPs). Purified polypeptide fragments comprising most of Gag spontaneously assemble in vitro at pH 6.5 into VLPs lacking a membrane, a process that r...

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Hlavní autoři: Ma, Yu May, Vogt, Volker M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC303394/
https://ncbi.nlm.nih.gov/pubmed/14671087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.52-60.2004
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