Reduced Simian Immunodeficiency Virus Replication in Macrophages of Sooty Mangabeys Is Associated with Increased Expression of Host Restriction Factors

Macrophages are target cells of HIV/SIV infection that may play a role in AIDS pathogenesis and contribute to the long-lived reservoir of latently infected cells during antiretroviral therapy (ART). In previous work, we and others have shown that during pathogenic SIV infection of rhesus macaques (R...

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Veröffentlicht in:J Virol
Hauptverfasser: Mir, Kiran D., Mavigner, Maud, Wang, Charlene, Paiardini, Mirko, Sodora, Donald L., Chahroudi, Ann M., Bosinger, Steven E., Silvestri, Guido
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580171/
https://ncbi.nlm.nih.gov/pubmed/26202248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00710-15
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