Simian Immunodeficiency Virus-Induced Alterations in Monocyte Production of Tumor Necrosis Factor Alpha Contribute to Reduced Immune Activation in Sooty Mangabeys

Human immunodeficiency virus type 1 (HIV-1) infection is characterized by persistent viral replication in the context of CD4(+) T cell depletion and elevated immune activation associated with disease progression. In contrast, simian immunodeficiency virus (SIV) infection of African-origin sooty mang...

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Detalhes bibliográficos
Main Authors: Mir, Kiran D., Bosinger, Steven E., Gasper, Melanie, Ho, On, Else, James G., Brenchley, Jason M., Kelvin, David J., Silvestri, Guido, Hu, Shiu-lok, Sodora, Donald L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416282/
https://ncbi.nlm.nih.gov/pubmed/22553338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06813-11
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