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RIG-I Mediates an Antiviral Response to Crimean-Congo Hemorrhagic Fever Virus
In the cytoplasm, the retinoic acid-inducible gene I (RIG-I) senses the RNA genomes of several RNA viruses. RIG-I binds to viral RNA, eliciting an antiviral response via the cellular adaptor MAVS. Crimean-Congo hemorrhagic fever virus (CCHFV), a negative-sense RNA virus with a 5′-monophosphorylated...
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| Publicado en: | J Virol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4580164/ https://ncbi.nlm.nih.gov/pubmed/26223644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01643-15 |
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