Soluble Envelope Glycoprotein Trimers from a CD4-Independent HIV-1 Elicit Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies in Guinea Pigs

CD4-independent HIV-1 variants can infect coreceptor-expressing cells lacking CD4. The envelope (Env) glycoproteins on these HIV-1 variants expose a coreceptor binding site that overlaps some CD4-induced (CD4i) epitopes. Reports have demonstrated that CD4i antibodies mediate antibody-dependent cellu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Murray, Marta K., Teran, Victor A., Chapleau, Jean-Philippe, Wang, Baomin, Kim, Su Hyon, LaBranche, Celia C., Richard, Jonathan, Montefiori, David C., Finzi, Andrés, Yuan, Wen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2015
Gaiak:
Vaccines and Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580154/
https://ncbi.nlm.nih.gov/pubmed/26246571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01642-15
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