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BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells

BACKGROUND: MicroRNA-200 (miR-200) suppresses the epithelial-mesenchymal transition of various cancer cells, including lung adenocarcinoma cells. We found that bone morphogenetic protein 4 (BMP4) was decreased in miR-200-overexpressing cells and epithelial-like lung cancer cells. In this study, we i...

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Publicado en:Mol Cancer
Autores principales: Kim, Jeong Seon, Kurie, Jonathan M., Ahn, Young-Ho
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580148/
https://ncbi.nlm.nih.gov/pubmed/26395571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0441-y
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