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Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord

BACKGROUND: Morphine-induced tolerance is associated with the spinal neuroinflammation. The aim of this study was to explore the effects of oral administration of the pioglitazone, the peroxisome proliferator activated receptor gamma (PPAR-γ) agonist, on the morphine-induced neuroinflammation in the...

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Publicado en:J Biomed Sci
Autores principales: Charkhpour, Mohammad, Ghavimi, Hamed, Ghanbarzadeh, Saeed, Yousefi, Bahman, Khorrami, Arash, Mesgari, Mehran, Hassanzadeh, Kambiz
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580127/
https://ncbi.nlm.nih.gov/pubmed/26394827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0187-2
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