Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord

BACKGROUND: Morphine-induced tolerance is associated with the spinal neuroinflammation. The aim of this study was to explore the effects of oral administration of the pioglitazone, the peroxisome proliferator activated receptor gamma (PPAR-γ) agonist, on the morphine-induced neuroinflammation in the...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Charkhpour, Mohammad, Ghavimi, Hamed, Ghanbarzadeh, Saeed, Yousefi, Bahman, Khorrami, Arash, Mesgari, Mehran, Hassanzadeh, Kambiz
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580127/
https://ncbi.nlm.nih.gov/pubmed/26394827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0187-2
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