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Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord

BACKGROUND: Morphine-induced tolerance is associated with the spinal neuroinflammation. The aim of this study was to explore the effects of oral administration of the pioglitazone, the peroxisome proliferator activated receptor gamma (PPAR-γ) agonist, on the morphine-induced neuroinflammation in the...

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Vydáno v:J Biomed Sci
Hlavní autoři: Charkhpour, Mohammad, Ghavimi, Hamed, Ghanbarzadeh, Saeed, Yousefi, Bahman, Khorrami, Arash, Mesgari, Mehran, Hassanzadeh, Kambiz
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580127/
https://ncbi.nlm.nih.gov/pubmed/26394827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0187-2
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