Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord

BACKGROUND: Morphine-induced tolerance is associated with the spinal neuroinflammation. The aim of this study was to explore the effects of oral administration of the pioglitazone, the peroxisome proliferator activated receptor gamma (PPAR-γ) agonist, on the morphine-induced neuroinflammation in the...

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Bibliografiske detaljer
Udgivet i:J Biomed Sci
Main Authors: Charkhpour, Mohammad, Ghavimi, Hamed, Ghanbarzadeh, Saeed, Yousefi, Bahman, Khorrami, Arash, Mesgari, Mehran, Hassanzadeh, Kambiz
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580127/
https://ncbi.nlm.nih.gov/pubmed/26394827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0187-2
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