HMGB1 release triggered by the interaction of live retinal cells and uveitogenic T cells is Fas/FasL activation-dependent

BACKGROUND: It is not clear how invading autoreactive T cells initiate the pathogenic process inside the diseased organ in T cell-mediated organ-specific autoimmune disease. In experimental autoimmune uveitis (EAU) induced by adoptive transfer of interphotoreceptor retinoid-binding protein (IRBP)-sp...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Neuroinflammation
Auteurs principaux: Jiang, Guomin, Wang, Yunsong, Yun, Juan, Hajrasouliha, Amir Reza, Zhao, Yuan, Sun, Deming, Kaplan, Henry J, Shao, Hui
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579830/
https://ncbi.nlm.nih.gov/pubmed/26394985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0389-2
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