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PD-L1(hi) retinal pigment epithelium (RPE) cells elicited by inflammatory cytokines induce regulatory activity in uveitogenic T cells

We previously reported that after exposure to inflammatory cytokines, such as IL-17 and IFN-γ, RPE cells express increased amounts of suppressor of cytokine signaling, leading to general suppression of the inflammatory response. Here, we demonstrate that RPE cells expressed increased levels of PD-L1...

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Détails bibliographiques
Auteurs principaux: Ke, Yan, Sun, Deming, Jiang, Guomin, Kaplan, Henry J., Shao, Hui
Format: Artigo
Langue:Inglês
Publié: Society for Leukocyte Biology 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996892/
https://ncbi.nlm.nih.gov/pubmed/20739617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0610332
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