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HMGB1 is an early and critical mediator in an animal model of uveitis induced by IRBP-specific T cells

It is largely unknown how invading autoreactive T cells initiate the pathogenic process inside the diseased organ in organ-specific autoimmune disease. In this study, we used a chronic uveitis disease model in mice—EAU—induced by adoptive transfer of uveitogenic IRBP-specific T cells and showed that...

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Detalhes bibliográficos
Main Authors: Jiang, Guomin, Sun, Deming, Yang, Huan, Lu, Qingxian, Kaplan, Henry J., Shao, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958740/
https://ncbi.nlm.nih.gov/pubmed/24374967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0613337
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