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Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling
Defective hepatic insulin receptor (IR) signalling is a pathogenic manifestation of metabolic disorders including obesity and diabetes. The endo/lysosomal trafficking system may coordinate insulin action and nutrient homeostasis by endocytosis of IR and the autophagic control of intracellular nutrie...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4579570/ https://ncbi.nlm.nih.gov/pubmed/26387534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9283 |
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