Spatiotemporal Targeting of a Dual-Ligand Nanoparticle to Cancer Metastasis

Various targeting strategies and ligands have been employed to direct nanoparticles to tumors that upregulate specific cell-surface molecules. However, tumors display a dynamic, heterogeneous microenvironment, which undergoes spatiotemporal changes including the expression of targetable cell-surface...

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Veröffentlicht in:ACS Nano
Hauptverfasser: Doolittle, Elizabeth, Peiris, Pubudu M., Doron, Gilad, Goldberg, Amy, Tucci, Samantha, Rao, Swetha, Shah, Shruti, Sylvestre, Meilyn, Govender, Priya, Turan, Oguz, Lee, Zhenghong, Schiemann, William P., Karathanasis, Efstathios
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579532/
https://ncbi.nlm.nih.gov/pubmed/26203676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b01552
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