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Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism
Antidepressants often disrupt sleep. Vortioxetine, a multimodal antidepressant acting through serotonin (5-HT) transporter (SERT) inhibition, 5-HT(3), 5-HT(7) and 5-HT(1D) receptor antagonism, 5-HT(1B) receptor partial agonism, and 5-HT(1A) receptor agonism, had fewer incidences of sleep-related adv...
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| Pubblicato in: | J Psychopharmacol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SAGE Publications
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4579402/ https://ncbi.nlm.nih.gov/pubmed/26174134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881115592347 |
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