Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA

The VAR2CSA protein of Plasmodium falciparum is transported to and expressed on the infected erythrocyte surface where it plays a key role in placental malaria (PM). It is the current leading candidate for a vaccine to prevent PM. However, the antigenic polymorphism integral to VAR2CSA poses a chall...

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Bibliografiske detaljer
Udgivet i:	PLoS One
Main Authors:	Doritchamou, Justin, Sabbagh, Audrey, Jespersen, Jakob S., Renard, Emmanuelle, Salanti, Ali, Nielsen, Morten A., Deloron, Philippe, Tuikue Ndam, Nicaise
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science 2015
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4579133/ https://ncbi.nlm.nih.gov/pubmed/26393516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137695
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Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA

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