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Systematic Prediction of Scaffold Proteins Reveals New Design Principles in Scaffold-Mediated Signal Transduction

Scaffold proteins play a crucial role in facilitating signal transduction in eukaryotes by bringing together multiple signaling components. In this study, we performed a systematic analysis of scaffold proteins in signal transduction by integrating protein-protein interaction and kinase-substrate re...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Hu, Jianfei, Neiswinger, Johnathan, Zhang, Jin, Zhu, Heng, Qian, Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578958/
https://ncbi.nlm.nih.gov/pubmed/26393507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004508
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