A Novel Bmal1 Mutant Mouse Reveals Essential Roles of the C-Terminal Domain on Circadian Rhythms

The mammalian circadian clock is an endogenous biological timer comprised of transcriptional/translational feedback loops of clock genes. Bmal1 encodes an indispensable transcription factor for the generation of circadian rhythms. Here, we report a new circadian mutant mouse from gene-trapped embryo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Park, Noheon, Kim, Hee-Dae, Cheon, Solmi, Row, Hansang, Lee, Jiyeon, Han, Dong-Hee, Cho, Sehyung, Kim, Kyungjin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578957/
https://ncbi.nlm.nih.gov/pubmed/26394143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138661
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