Leukocyte Mitochondrial DNA Copy Number Is Associated with Chronic Obstructive Pulmonary Disease

BACKGROUND: Oxidative stress is known to be involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Evidence suggests that leukocytes mitochondria DNA (mtDNA) is susceptible to undergo mutations, insertions, or depletion in response to reactive oxidative stress (ROS). We hypoth...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Liu, Shih-Feng, Kuo, Ho-Chang, Tseng, Ching-Wan, Huang, Hung-Tu, Chen, Yung-Che, Tseng, Chia-Cheng, Lin, Meng-Chih
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578933/
https://ncbi.nlm.nih.gov/pubmed/26394041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138716
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