Leukocyte Mitochondrial DNA Copy Number Is Associated with Chronic Obstructive Pulmonary Disease

BACKGROUND: Oxidative stress is known to be involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Evidence suggests that leukocytes mitochondria DNA (mtDNA) is susceptible to undergo mutations, insertions, or depletion in response to reactive oxidative stress (ROS). We hypoth...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Shih-Feng, Kuo, Ho-Chang, Tseng, Ching-Wan, Huang, Hung-Tu, Chen, Yung-Che, Tseng, Chia-Cheng, Lin, Meng-Chih
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578933/
https://ncbi.nlm.nih.gov/pubmed/26394041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138716
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