Leukocyte Mitochondrial DNA Copy Number Is Associated with Chronic Obstructive Pulmonary Disease

BACKGROUND: Oxidative stress is known to be involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Evidence suggests that leukocytes mitochondria DNA (mtDNA) is susceptible to undergo mutations, insertions, or depletion in response to reactive oxidative stress (ROS). We hypoth...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Liu, Shih-Feng, Kuo, Ho-Chang, Tseng, Ching-Wan, Huang, Hung-Tu, Chen, Yung-Che, Tseng, Chia-Cheng, Lin, Meng-Chih
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578933/
https://ncbi.nlm.nih.gov/pubmed/26394041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138716
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