Insulin activates EGFR by stimulating its interaction with IGF-1R in low-EGFR-expressing TNBC cells

The expression of epidermal growth factor receptor (EGFR) is an important diagnostic marker for triple-negative breast cancer (TNBC) cells, which lack three hormonal receptors: estrogen and progesterone receptors as well as epidermal growth factor receptor 2. EGFR transactivation can cause drug resi...

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Bibliografiske detaljer
Udgivet i:BMB Rep
Main Authors: Shin, Miyoung, Yang, Eun Gyeong, Song, Hyun Kyu, Jeon, Hyesung
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Biochemistry and Molecular Biology 2015
Fag:
Research-Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578621/
https://ncbi.nlm.nih.gov/pubmed/25341922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2015.48.6.157
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