Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer

BACKGROUND: APC mutations (APC-mt) occur in ∼70% of colorectal cancers (CRCs), but their relationship to prognosis is unclear. METHODS: APC prognostic value was evaluated in 746 stage I–IV CRC patients, stratifying for tumour location and microsatellite instability (MSI). Microarrays were used to id...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Br J Cancer
Hlavní autoři: Jorissen, Robert N, Christie, Michael, Mouradov, Dmitri, Sakthianandeswaren, Anuratha, Li, Shan, Love, Christopher, Xu, Zheng-Zhou, Molloy, Peter L, Jones, Ian T, McLaughlin, Stephen, Ward, Robyn L, Hawkins, Nicholas J, Ruszkiewicz, Andrew R, Moore, James, Burgess, Antony W, Busam, Dana, Zhao, Qi, Strausberg, Robert L, Lipton, Lara, Desai, Jayesh, Gibbs, Peter, Sieber, Oliver M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Genetics & Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578087/
https://ncbi.nlm.nih.gov/pubmed/26305864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.296
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky