Impaired T-bet-pSTAT1α and perforin-mediated immune responses in the tumoral region of lung adenocarcinoma

BACKGROUND: In spite of modern therapies for non-small-cell lung cancer (NSCLC), prognosis for many patients is still poor and survival rates are low. Immunotherapy is the possibility to improve the lung immune response surrounding the tumour. However, this approach requires detailed understanding o...

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Publicat a:Br J Cancer
Autors principals: Andreev, Katerina, Denis Iulian Trufa, I, Siegemund, Raphaela, Rieker, Ralf, Hartmann, Arndt, Schmidt, Joachim, Sirbu, Horia, Finotto, Susetta
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Translational Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578079/
https://ncbi.nlm.nih.gov/pubmed/26348446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.255
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