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Impact of Nucleoporin-Mediated Chromatin Localization and Nuclear Architecture on HIV Integration Site Selection

It has been known for a number of years that integration sites of human immunodeficiency virus type 1 (HIV-1) DNA show a preference for actively expressed chromosomal locations. A number of viral and cellular proteins are implicated in this process, but the underlying mechanism is not clear. Two rec...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Wong, Richard W., Mamede, João I., Hope, Thomas J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577903/
https://ncbi.nlm.nih.gov/pubmed/26136574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01669-15
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