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Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding

Nucleoporin proteins (Nups) have been proposed to mediate spatial and temporal chromatin organization during gene regulation. Nevertheless, the molecular mechanisms in mammalian cells are not well understood. Here, we report that Nucleoporin 153 (NUP153) interacts with the chromatin architectural pr...

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Foilsithe in:Nat Commun
Main Authors: Kadota, Shinichi, Ou, Jianhong, Shi, Yuming, Lee, Jeannie T., Sun, Jiayu, Yildirim, Eda
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248104/
https://ncbi.nlm.nih.gov/pubmed/32451376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16394-3
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