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Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding

Nucleoporin proteins (Nups) have been proposed to mediate spatial and temporal chromatin organization during gene regulation. Nevertheless, the molecular mechanisms in mammalian cells are not well understood. Here, we report that Nucleoporin 153 (NUP153) interacts with the chromatin architectural pr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kadota, Shinichi, Ou, Jianhong, Shi, Yuming, Lee, Jeannie T., Sun, Jiayu, Yildirim, Eda
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248104/
https://ncbi.nlm.nih.gov/pubmed/32451376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16394-3
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