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Brain Invasion by Mouse Hepatitis Virus Depends on Impairment of Tight Junctions and Beta Interferon Production in Brain Microvascular Endothelial Cells

Coronaviruses (CoVs) have shown neuroinvasive properties in humans and animals secondary to replication in peripheral organs, but the mechanism of neuroinvasion is unknown. The major aim of our work was to evaluate the ability of CoVs to enter the central nervous system (CNS) through the blood-brain...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Bleau, Christian, Filliol, Aveline, Samson, Michel, Lamontagne, Lucie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577898/
https://ncbi.nlm.nih.gov/pubmed/26202229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01501-15
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