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Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cells

BACKGROUND: Cerebral hypoxia/ischemia (H/I) is an important stress factor involved in the disruption of the blood–brain barrier (BBB) following stroke injury, yet the cellular and molecular mechanisms on how the human BBB responds to such injury remains unclear. In this study, we investigated the ce...

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Bibliografische gegevens
Gepubliceerd in:Fluids Barriers CNS
Hoofdauteurs: Page, Shyanne, Munsell, Alli, Al-Ahmad, Abraham J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057206/
https://ncbi.nlm.nih.gov/pubmed/27724968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-016-0042-1
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