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Inhibition of Ebola and Marburg Virus Entry by G Protein-Coupled Receptor Antagonists

Filoviruses, consisting of Ebola virus (EBOV) and Marburg virus (MARV), are among the most lethal infectious threats to mankind. Infections by these viruses can cause severe hemorrhagic fevers in humans and nonhuman primates with high mortality rates. Since there is currently no vaccine or antiviral...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Cheng, Han, Lear-Rooney, Calli M., Johansen, Lisa, Varhegyi, Elizabeth, Chen, Zheng W., Olinger, Gene G., Rong, Lijun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577884/
https://ncbi.nlm.nih.gov/pubmed/26202243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01337-15
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