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Zaire Ebola virus entry into human dendritic cells is insensitive to cathepsin L inhibition

Cathepsins B and L contribute to Ebola virus (EBOV) entry into Vero cells and MEFs. However, the role of cathepsins in EBOV-infection of human dendritic cells (DCs), important targets of infection in vivo, remains undefined. Here, EBOV-like particles containing a beta-lactamase-VP40 fusion reporter...

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Détails bibliographiques
Auteurs principaux: Martinez, Osvaldo, Johnson, Joshua, Manicassamy, Balaji, Rong, Lijun, Olinger, Gene G., Hensley, Lisa E., Basler, Christopher F.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996272/
https://ncbi.nlm.nih.gov/pubmed/19775255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2009.01385.x
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