The microRNA-212/132 cluster regulates B cell development by targeting Sox4

MicroRNAs have emerged as key regulators of B cell fate decisions and immune function. Deregulation of several microRNAs in B cells leads to the development of autoimmune disease and cancer in mice. We demonstrate that the microRNA-212/132 cluster (miR-212/132) is induced in B cells in response to B...

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Vydáno v:J Exp Med
Hlavní autoři: Mehta, Arnav, Mann, Mati, Zhao, Jimmy L., Marinov, Georgi K., Majumdar, Devdoot, Garcia-Flores, Yvette, Du, Xiaomi, Erikci, Erdem, Chowdhury, Kamal, Baltimore, David
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577845/
https://ncbi.nlm.nih.gov/pubmed/26371188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150489
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