Transcriptional repression of ANGPT1 by histone H3K9 demethylase KDM3B

Here we report that the H3K9 demethylase KDM3B represses transcription of the angiogenesis regulatory gene, ANGPT1. Negative regulation of ANGPT1 by KDM3B is independent of its Jumonji (JmjC) domain-mediated H3K9 demethylase activity. We demonstrate that KDM3B downregulates ANGPT1 via interaction wi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMB Rep
Egile Nagusiak: Han, Arim, Chae, Yun-Cheol, Park, Jin Woo, Kim, Kee-Beom, Kim, Ji-Young, Seo, Sang-Beom
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Korean Society for Biochemistry and Molecular Biology 2015
Gaiak:
Research-Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577290/
https://ncbi.nlm.nih.gov/pubmed/25413303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2015.48.7.188
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