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Improvement of fluvastatin bioavailability by loading on nanostructured lipid carriers

The aim of this study is to prepare fluvastatin nanostructured lipid carriers (FLV-NLCs) in order to find an innovative way to alleviate FLV-associated disadvantages. The limitations include poor solubility and extensive first-pass metabolism, resulting in low (30%) bioavailability and short elimina...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Int J Nanomedicine
Päätekijät: El-Helw, Abdel-Rahim M, Fahmy, Usama A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577263/
https://ncbi.nlm.nih.gov/pubmed/26396513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S91556
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