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Improvement of fluvastatin bioavailability by loading on nanostructured lipid carriers
The aim of this study is to prepare fluvastatin nanostructured lipid carriers (FLV-NLCs) in order to find an innovative way to alleviate FLV-associated disadvantages. The limitations include poor solubility and extensive first-pass metabolism, resulting in low (30%) bioavailability and short elimina...
Gespeichert in:
| Veröffentlicht in: | Int J Nanomedicine |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4577263/ https://ncbi.nlm.nih.gov/pubmed/26396513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S91556 |
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